Tension-dependent structures in a stretch-activated system
نویسندگان
چکیده
منابع مشابه
Myosin light chain phosphorylation and tension development in stretch-activated arterial smooth muscle.
Phosphorylation of the 20 000-Da light chain of myosin in functionally different porcine carotid arteries was determined, with use of two-dimensional gel electrophoresis. Stretching arteries to 1.7 times their resting length resulted in maximal phosphorylation. Intracellular Ca2+ was mobilized for stretch-induced light chain phosphorylation. Releasing the stretch from the arteries produced acti...
متن کاملStretch-Activated Arrhythmias
Background. Although the existence of myocardial mechanoelectrical feedback is well established, the mechanism of arrhythmia induction by ventricular dilatation or stretch remains insuffliciently defined. In particular, controversy exists when comparing the arrhythmogenic potential of chronic versus acute myocardial stretch. Also, assessment of cellular electrophysiological effects of myocardia...
متن کاملSensing tension: recognizing ENaC as a stretch sensor.
Homeostasis demands the integration and processing of a myriad of different input signals from a variety of sources. Regulation of central blood pressure is one such homeostatic system that depends critically on both volumetric and hemodynamic information. A common element for cardiovascular data transfer is sensing mechanical alterations such as cellular volume changes, changes in shear stress...
متن کاملStretch activated ion channels in ventricular myocytes.
Patch-clamp recordings from ventricular myocytes of neonatal rats identified ionic channels that open in response to membrane stretch caused by negative pressures (1 to 6 cm Hg) in the electrode. The stretch response, consisting of markedly increased channel opening frequency, was maintained, with some variability, during long (greater than 40 seconds) stretch applications. The channels have a ...
متن کاملStretch-induced myosin light chain phosphorylation and stretch-release-induced tension development in arterial smooth muscle.
Stretching arteries from resting length to 1.7 times the resting length increased myosin light chain phosphorylation from 40 to 70% in a graded fashion, reaching a plateau at 1.6 times the resting length. When the fully stretched arteries were released, active tension developed without any exogenous stimulating agent. This stretch-release-induced tension approached the same magnitude as that of...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bodywork and Movement Therapies
سال: 2020
ISSN: 1360-8592
DOI: 10.1016/j.jbmt.2019.12.001